Bioscientifica Proceedings

With the advent of next generation sequencing platforms (RNA-seq), transcriptional profiling permits the characterization of millions of RNAs from even the most limiting samples like early embryos. High-throughput RNA-seq can generate over 600 gigabases (Gb) in a single sequencing run, providing a near-complete record of all of the genes expressed in a sample at the time of collection. Condensing and finding coherence in the immense amount of raw data generated by transc...